Signatures of Cardiovascular Health Derived from Integrated Biomics, Environment and Lifestyle – Findings from the Canadian Alliance for Healthy Hearts and Minds – CARTaGENE Cohort

Status Completed
Start date 2019
Location Quebec
Researcher Friedrich, Matthias
Associated institution The Research Institute of the McGill University Health Centre and McGill University
Summary

Cardiovascular disease remains one of the leading causes of illness and death worldwide. This project combined magnetic resonance imaging (MRI), genetic data, and information on lifestyle and environmental factors to better understand the determinants of cardiovascular health. Using data from CARTaGENE and the Canadian Alliance for Healthy Hearts and Minds (CAHHM), researchers developed new approaches to study early signs of cardiovascular disease before symptoms appear.

The research helped establish reference values for heart structure and function in a diverse population and showed that cardiovascular risk factors are associated with subtle brain changes detected by MRI as well as reduced cognitive performance. These findings contribute to improving the early detection of cardiovascular disease and support the development of more personalized prevention strategies.

Themes
  • Chronic diseases
  • Genetics and genomics
Data types
  • Biochemical and hematological data
  • Biological samples
  • Genetic data
  • Physical and cognitive measures
  • Questionnaire data

Related resources