Publications
2017
Tremblay M, Rouleau G, Deep genealogical analysis of a large cohort of participants in the CARTaGENE project (Quebec, Canada)., Annals of Human Biology
Dias C, Giordano M, Frechette R, Bellone S, Polychronakos C, Legault L, Deal CL, Goodyer CG, Genetic variations at the human growth hormone receptor (GHR) gene locus are associated with idiopathic short stature, J Cell Mol Med
Bernatsky S, Smargiassi A, Joseph L, Awadalla P, Colmegna I, Hudson M, Fritzler MJ, Industrial air emissions, and proximity to major industrial emitters, are associated with anti-citrullinated protein antibodies, Environ Res.
2016
S. Troyanov, C. Delmas-Frenette, G. Bollee, S. Youhanna, V. Bruat, P. Awadalla, O. Devuyst and F. Madore, Clinical, Genetic, and Urinary Factors Associated with Uromodulin Excretion, Clin J Am Soc Nephrol 11(1): 62-69
Hodgkinson A, Grenier JC, Gbeha E, Awadalla P. A, Haplotype-based normalization technique for the analysis and detection of allele specific expression, BMC Bioinformatics 17(1): 364
N. D. Merner, A. Mercado, A. R. Khanna, A. Hodgkinson, V. Bruat, P. Awadalla, G. Gamba, G. A. Rouleau and K. T. Kahle, Gain-of-function missense variant in SLC12A2, encoding the bumetanide-sensitive NKCC1 cotransporter, identified in human schizophrenia, J Psychiatr Res 77: 22-26
R. Goupil, D. Dupuis, S. Troyanov, F. Madore and M. Agharazii, Heart rate dependent and independent effects of beta-blockers on central hemodynamic parameters: a propensity score analysis, J Hypertens 34(8): 1535-1543
R. Goupil, D. Dupuis, M. Agharazii, P. Hamet, S. Troyanov and F. Madore, Central blood pressures in early chronic kidney disease: an analysis of CARTaGENE, Nephrol Dial Transplant
S. S. Anand, J. V. Tu, P. Awadalla, S. Black, C. Boileau, D. Busseuil, D. Desai, J. P. Despres, R. J. de Souza, T. Dummer, S. Jacquemont, B. Knoppers, E. Larose, S. A. Lear, F. Marcotte, A. R. Moody, L. Parker, P. Poirier, P. J. Robson, E. E. Smith, J. J., Rationale, design, and methods for Canadian alliance for healthy hearts and minds cohort study (CAHHM) - a Pan Canadian cohort study, BMC Public Health 16: 650
2015
C. S. Moura, S. S. Daskalopoulou, L. E. Levesque, S. Bernatsky, M. Abrahamowicz, M. A. Tsadok, S. Rajabi and L. Pilote, Comparison of the Effect of Thiazide Diuretics and Other Antihypertensive Drugs on Central Blood Pressure: Cross-Sectional Analysis Among Nondiabetic Patients, J Clin Hypertens (Greenwich) 17(11): 848-854
J. G. Hussin, A. Hodgkinson, Y. Idaghdour, J. C. Grenier, J. P. Goulet, E. Gbeha, E. Hip-Ki and P. Awadalla, Recombination affects accumulation of damaging and disease-associated mutations in human populations, Nat Genet 47(4): 400-404
R. El-Bikai, M. R. Tahir, J. Tremblay, M. Joffres, O. Seda, L. Sedova, P. Awadalla, C. Laberge, B. M. Knoppers, P. Dumas, D. Gaudet, L. G. Ste-Marie and P. Hamet, Association of age-dependent height and bone mineral density decline with increased arterial stiffness and rate of fractures in hypertensive individuals, J Hypertens 33(4): 727-735
2014
K. T. Kahle, N. D. Merner, P. Friedel, L. Silayeva, B. Liang, A. Khanna, Y. Shang, P. Lachance-Touchette, C. Bourassa, A. Levert, P. A. Dion, B. Walcott, D. Spiegelman, A. Dionne-Laporte, A. Hodgkinson, P. Awadalla, H. Nikbakht, J. Majewski, P. Cossette, Genetically encoded impairment of neuronal KCC2 cotransporter function in human idiopathic generalized epilepsy, EMBO Rep 15(7): 766-774
J. C. Verhave, S. Troyanov, F. Mongeau, L. Fradette, J. Bouchard, P. Awadalla and F. Madore, Prevalence, awareness, and management of CKD and cardiovascular risk factors in publicly funded health care, Clin J Am Soc Nephrol 9(4): 713-719
A. Hodgkinson, Y. Idaghdour, E. Gbeha, J. C. Grenier, E. Hip-Ki, V. Bruat, J. P. Goulet, T. de Malliard and P. Awadalla, High-resolution genomic analysis of human mitochondrial RNA sequence variation, Science 344(6182): 413-415
2013
P. Awadalla, C. Boileau, Y. Payette, Y. Idaghdour, J. P. Goulet, B. Knoppers, P. Hamet, C. Laberge and C. A. Project, Cohort profile of the CARTaGENE study: Quebec's population-based biobank for public health and personalized genomics, Int J Epidemiol 42(5): 1285-1299
2011
S. Fortin, S. Pathmasiri, R. Grintuch and M. Deschenes, Access arrangements' for biobanks: a fine line between facilitating and hindering collaboration, Public Health Genomics 14(2): 104-114
2007
B. Godard, J. Marshall and C. Laberge, Community engagement in genetic research: results of the first public consultation for the Quebec CARTaGENE project, Community Genet 10(3): 147-158
2006
Y. Joly and B. M. Knoppers, Pharmacogenomic data sample collection and storage: ethical issues and policy approaches, Pharmacogenomics 7(2): 219-226
2004
B. Godard, J. Marshall, C. Laberge and B. M. Knoppers, Strategies for consulting with the community: the cases of four large-scale genetic databases, Sci Eng Ethics 10(3): 457-477
Projects
2016
Genomic Analysis of the Mitochondrial Transcriptome Principal Investigator: Alan Hogkinson
Affiliation: King's College London
Deciphering the Genetic background of Restless Legs Syndrome Principal Investigator: Guy Rouleau
Affiliation: Institut neurologique de Montréal, Université McGill
Genomic follow-up of the susceptibility loci for schizophrenia and bipolar disorder in multi-affected families of Eastern Quebec Principal Investigator: Michel Maziade
Affiliation: Université Laval
Poor sleep and mental health: independent or overlapping risk factors for heart diseases? Principal Investigator: Norbert Schmitz
Affiliation: Institut de santé mentale Douglas, Université McGill
2015
Simultaneous systematic monitoring of hormonal pathways in bipolar disorder using LC-based targeted and untargeted metabolomics Principal Investigator: Dajana Vuckovic
Affiliation: Université Concordia
Clinical implementation and Outcomes Evaluation of Blood-Based biomarkers for COPD management Principal Investigator: Elizabeth MacNamara
Affiliation: Hôpital général juif
Identification of genes involved in adolescent idiopathic Scoliosis Principal Investigator: Alain Moreau
Affiliation: CHU Sainte-Justine
2014
Evaluation of coronary vascular disease among high cardiovascular risk patients in CARTaGENE Principal Investigator: Robert Sanchez
Affiliation: Regeneron
Canadian Alliance for Healthy Hearts and Minds – Development of community health and health services profiles Principal Investigator: Jack Tu
Affiliation: Sunnybrook Health Sciences Centre
Human Growth Hormone Receptor: regulation of expression during development Principal Investigator: Cynthia Goodyer
Affiliation: Université McGill
Génétique de la Rhinosinusite chronique avec polypose nasale Principal Investigator: Martin Desrosiers
Affiliation: CHUM
Conséquences médicales de l’intégration chromosomique de l’herpès virus humain 6 Principal Investigator: Louis Flamand
Affiliation: Université Laval
The genome-wide association study of the principal components of the metabolic syndrome enriched with albumin/creatinine ratio regarding the OPTI-THERA research project Principal Investigator: Pavel Hamet
Affiliation: CHUM
The association between type II diabetes and physical activity in the Canadian Partnership for Tomorrow Project Principal Investigator: Zhijie (Michael) Yu
Affiliation: Dalhousie University
Exploring the potential of CARTaGENE databanks for GIS-based epidemiology: a pilot study Principal Investigator: Philip Awadalla
Affiliation: CHU Sainte-Justine, Université de Montréal
Vegetarian diet, the metabolic syndrome, obesity and inflammatory status Principal Investigator: Isabel Fortier
Affiliation: Maelstrom, Université McGill
Comparative Effectiveness Research in the Canadian Partnership for Tomorrow Cohort Principal Investigator: Sasha Bernatsky
Affiliation: Centre de santé de l’Université McGill
2013
Plateforme d’Innovation en Génomique des Scolioses Pédiatriques (GSP) : Des Gènes aux Tests - Diagnostiques Complets Principal Investigator: Alain Moreau
Affiliation: CHU Ste-Justine
Molecular dissection of congenital heart disease in the French Canadian population Principal Investigator: Gregor Andelfinger
Affiliation: CHU Ste-Justine
Étude bien-être émotionnel, facteurs métaboliques et l’état de santé Principal Investigator: Norbert Schmitz
Affiliation: Institut de santé mentale Douglas, Université McGill
Prévalence de l’insuffisance rénale chronique dans la cohorte CARTaGENE (2) Principal Investigator: François Madore
Affiliation: Hôpital Sacré-Coeur
2012
Test de l’accumulation de mutations délétères lors d’expansions spatiales par séquençage d’exomes Principal Investigator: Laurent Excoffier
Affiliation: Université de Berne, Suisse
Comparative Effectiveness Research in the Canadian Partnership for Tomorrow Cohort Principal Investigator: Sasha Bernatsky
Affiliation: Centre de santé de l’Université McGill
Analyse des caractéristiques généalogiques des participants au projet CARTaGENE Principal Investigator: Marc Tremblay
Affiliation: Université du Québec à Chicoutimi
Environment, Epigenetics, and Rheumatic Disease Principal Investigator: Sasha Bernatsky
Affiliation: Centre de santé de l’Université McGill
Conséquences médicales de l’intégration chromosomique de l’herpès virus humain 6 Principal Investigator: Louis Flamand
Affiliation: Université Laval
2011
Développement d’une plateforme pour le diagnostic moléculaire du syndrome de Zellweger au Québec Principal Investigator: Luigi Bouchard
Affiliation: Université de Sherbrooke
Caractérisation des contributions génomiques et environnementales à la variation des phénotypes cardiovasculaires et métaboliques dans la population du Québec Principal Investigator: Philip Awadalla
Affiliation: CHU Sainte-Justine, Université de Montréal
2010
Hypertension, ostéoporose et vieillissement accéléré Principal Investigator: Pavel Hamet
Affiliation: CHUM
Prévalence de l’insuffisance rénale chronique dans la cohorte CARTaGENE (1) Principal Investigator: François Madore
Affiliation: Hôpital Sacré-Coeur
2009
Methylmercury exposure and urinary metabolic profile in Cree people from Northern Quebec Principal Investigator: Pierre Ayotte
Affiliation: Centre de recherche du CHUQ, Université Laval